Parameters group studied (n = 10)

Renal tissue homogenate

TNF-α (ng/ml)

MDA (nmol/g)

XO (U/g)

NO (µmol/g)

MPO (U/g)

Normal control gp.

5.35^bcde ± 0.43

1.2^bcde ± 0.15

1.29^bcd ± 0.05

0.6^bcd ± 0.03

2.1^bcd ± 0.05

Diabetic gp.

17.78^acde ± 0.99

3.7^acde ± 0.41

1.97^acde ± 0.08

0.8^acde ± 0.02

3.7^acde ± 0.51

Ischemic reperfused (IR) gp.

19.47^abde ± 0.82

4.8^abde ± 0.5

2.1^abde ± 0.05

0.9^abde ±0.025

6.6^abde ± 0.27

Diabetic + I/R gp.

29.15^abce ± 0.65

6.6^abce ± 0.27

2.3^abce ± 0.03

1.3^abce ± 0.09

8.7^abce ± 0.41

Sitaglipten treated (Diabetic + I/R) gp.

6.52^abcd ± 0.72

1.7^abcd ± 0.3

1.3^bcd ± 0.09

0.6^bcd ± 0.04

2.3^bcd ± 0.41

F (p)

1758.387^* (<0.001)

410.522^* (<0.001)

538.407^* (<0.001)

356.989^* (<0.001)

616.495^* (<0.001)

LSD (5%)

0.667

0.311

0.057

0.040

0.327